Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
| Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY |
| Enrichment Score (ES) | -0.7439771 |
| Normalized Enrichment Score (NES) | -1.576805 |
| Nominal p-value | 0.004796163 |
| FDR q-value | 0.17484231 |
| FWER p-Value | 0.745 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PPP3CB | 6020156 | 1128 | 0.643 | -0.0326 | No | ||
| 2 | GRB2 | 6650398 | 1188 | 0.612 | -0.0090 | No | ||
| 3 | PTPRC | 130402 5290148 | 1547 | 0.456 | -0.0083 | No | ||
| 4 | MAP2K4 | 5130133 | 1821 | 0.367 | -0.0070 | No | ||
| 5 | RAC1 | 4810687 | 1942 | 0.331 | 0.0011 | No | ||
| 6 | RAF1 | 1770600 | 2375 | 0.227 | -0.0123 | No | ||
| 7 | MAPK8 | 2640195 | 3135 | 0.114 | -0.0481 | No | ||
| 8 | HRAS | 1980551 | 4798 | 0.029 | -0.1364 | No | ||
| 9 | PPP3CA | 4760332 6760092 | 5029 | 0.025 | -0.1476 | No | ||
| 10 | PLCG1 | 6020369 | 5664 | 0.017 | -0.1810 | No | ||
| 11 | ARHGAP6 | 2060121 | 6945 | 0.009 | -0.2495 | No | ||
| 12 | PIK3R1 | 4730671 | 7437 | 0.007 | -0.2756 | No | ||
| 13 | MAP2K1 | 840739 | 8060 | 0.005 | -0.3089 | No | ||
| 14 | ARHGAP5 | 2510619 3360035 | 9989 | -0.001 | -0.4127 | No | ||
| 15 | SOS1 | 7050338 | 11108 | -0.004 | -0.4727 | No | ||
| 16 | JUN | 840170 | 11404 | -0.005 | -0.4884 | No | ||
| 17 | NCF2 | 540129 2370441 2650133 | 11699 | -0.006 | -0.5040 | No | ||
| 18 | PIK3CA | 6220129 | 12684 | -0.010 | -0.5565 | No | ||
| 19 | CAMK2B | 2760041 | 13763 | -0.019 | -0.6137 | No | ||
| 20 | SHC1 | 2900731 3170504 6520537 | 13907 | -0.021 | -0.6205 | No | ||
| 21 | PRKCA | 6400551 | 13942 | -0.022 | -0.6213 | No | ||
| 22 | FOS | 1850315 | 14022 | -0.023 | -0.6246 | No | ||
| 23 | ARHGAP1 | 2810010 5270064 | 14636 | -0.036 | -0.6560 | No | ||
| 24 | NFATC1 | 510400 2320348 4050600 6180161 6290136 6620086 | 14962 | -0.050 | -0.6713 | No | ||
| 25 | FYN | 2100468 4760520 4850687 | 15761 | -0.116 | -0.7092 | No | ||
| 26 | ARFGAP1 | 4780364 5390358 | 16045 | -0.149 | -0.7179 | No | ||
| 27 | ZAP70 | 1410494 2260504 | 16061 | -0.152 | -0.7121 | No | ||
| 28 | PPP3CC | 2450139 | 16238 | -0.177 | -0.7138 | No | ||
| 29 | PTPN7 | 3450110 | 16799 | -0.293 | -0.7312 | Yes | ||
| 30 | ARFGAP3 | 3390717 | 16848 | -0.306 | -0.7204 | Yes | ||
| 31 | LAT | 3170025 | 16883 | -0.315 | -0.7084 | Yes | ||
| 32 | RALBP1 | 4780632 | 17268 | -0.439 | -0.7099 | Yes | ||
| 33 | NFKBIA | 1570152 | 17293 | -0.450 | -0.6915 | Yes | ||
| 34 | RELA | 3830075 | 17328 | -0.467 | -0.6729 | Yes | ||
| 35 | MAPK3 | 580161 4780035 | 17348 | -0.472 | -0.6533 | Yes | ||
| 36 | LCK | 3360142 | 17548 | -0.561 | -0.6394 | Yes | ||
| 37 | VAV1 | 6020487 | 17855 | -0.751 | -0.6230 | Yes | ||
| 38 | CD4 | 1090010 | 18045 | -0.930 | -0.5925 | Yes | ||
| 39 | MAP3K1 | 5360347 | 18135 | -1.031 | -0.5522 | Yes | ||
| 40 | CD3E | 3800056 | 18269 | -1.267 | -0.5039 | Yes | ||
| 41 | CD3D | 2810739 | 18272 | -1.277 | -0.4482 | Yes | ||
| 42 | ARHGAP4 | 1940022 | 18372 | -1.547 | -0.3858 | Yes | ||
| 43 | CD247 | 3800725 5720136 | 18457 | -1.820 | -0.3107 | Yes | ||
| 44 | CD3G | 2680288 | 18531 | -2.468 | -0.2067 | Yes | ||
| 45 | TRB@ | 3940292 | 18610 | -4.828 | 0.0003 | Yes |
